师资名录

庞燕

长聘教轨副教授

 

邮箱:yanpang@sjtu.edu.cn

庞燕,上海交通大学药学院长聘教轨副教授,课题组长,博士生导师,上海海外高层次引进人才,上海高校东方学者特聘教授,上海交通大学医学院双百人。博士毕业于上海交通大学化学化工学院,之后赴美国杜克大学Ashutosh Chilkoti教授课题组从事博士后研究,2016年加入麻省理工学院Robert Langer教授课题组,先后任高级博士后、研究科学家。2019年加入上海交通大学医学院先后任助理研究员、副研究员,2024年全职加入上海交通大学药学院。近五年,在国际高水平学术期刊上以通讯作者发表论文20余篇,包括Nat. Commun.、Sci. Adv.、Adv. Drug Delivery Rev.、Nano Today、ACS Nano、Small、Bioactive materials、Biomaterials等,相关工作被MIT news,Chemviews,Nature Communications Editors’ Highlights, Medindia,Techexplorist等报道。申请中国、美国和国际发明专利9项,授权2项。研究方向包括生物医用高分子水凝胶的设计合成及功能化、生物膜仿生药物递送系统的构建及应用,特别关注眼部相关疾病的诊治。

因科研工作需要,课题组长期招聘博士后、科研助理等,有意向者请联系:yanpang@sjtu.edu.cn。
招聘领域
1)化学背景:有机化学、高分子化学、药物化学;
2)材料学背景:高分子材料合成与改性、生物医用高分子材料;
3)药学与生物医学背景:药物递送、分子生物学、免疫等;
4)疾病诊治背景:眼部相关疾病(眼表角膜病、干眼症、青光眼、眼底新生血管、视神经损伤等)、肿瘤、衰老、炎症相关疾病等等。
学科方向:生物医用高分子及药物递送研究
Biomedical Polymers and Their Applications in Drug Delivery
1. 生物医用高分子水凝胶的设计合成及功能化
2. 生物膜仿生药物递送系统的构建
3. 眼部局部给体系的构建及疾病治疗
1. Wu, F. #, Ren, Y. S.#, Lv, W. Y., Liu, X. B., Wang, X. Y., Wang, C. H., Cao, Z. P., Liu, J. Y.*, Wei, J.*, Pang, Y.* Generating dual structurally and functionally skin-mimicking hydrogels by crosslinking cell-membrane compartments. Nat. Commun. 2024, 15, 802.
2. Chen, F. J., Zhang, M. M., Yang, F. M., Wang, L.*, Liu, J. Y.*, Liu, J. Q., Pang, Y.* Dual-antigen-displaying nanovaccines elicit synergistic immunoactivation for treating cancer and preventing infectious complications Small 2023, 2307748.
3. Fu, Z. Z., Wang, L., Guo, H. Y., Lin, S. S.*, Huang, W.*, Pang, Y.* Bacterial flagellum-drug nanoconjugates for carrier-free immunochemotherapy. Small 2023, 2306303.
4. Wang, C. H., Pang, Y.* Nano-based eye drop: Topical and noninvasive therapy for ocular diseases. Adv. Drug Deliver. Rev. 2023, 194, 114721.
5. Cao, Z. P.#, Liu, R.#, Wang, C. H., Lin, S. S., Wang, L., Pang, Y.* Fluorescence-activating and absorption-shifting nanoprobes for anaerobic tracking of gut microbiota derived vesicles. ACS Nano 2023, 17, 2279−2293.
6. Su, Y., Fan, X. Q.*, Pang, Y.* Nano-based ocular drug delivery systems: an insight into the preclinical/clinical studies and their potential in the treatment of posterior ocular diseases. Biomater. Sci. 2023, 11, 4490.
7. Wang, X. Y.#, Chen, L. B.#, Wang, X. L.#, Zhang, M. M., Yang, F. M., Wu, F., Liu, J. Y.*, Lu, L.*, Pang, Y.* Long-acting protective ocular surface by instilling adhesive dual-antiviral nanoparticles. Adv. Healthc. Mater. 2022, 2200283.
8. Zhang, M. M.#, Wang, L.#, Liu, J. Y.*, Pang, Y.* Envelope virus-mimetic nanovaccines by hybridizing bioengineered cell membranes with bacterial vesicles. iScience 2022, 25,104490.
9. Wang, Z. Q.#, Yu, Y.#, Wang, C. Q., Li, J.*, Pang, Y.* Advances in the application of nanomaterials to the treatment of melanoma. Pharmaceutics 2022, 14, 2090.
10. Ju, Y. H.#, Dai, X. C.#, Tang, Z. M.#, Ming, Z. Z., Ni, N., Zhu, D. Q., Zhang, J., Ma, B., Wang, J. J., Huang, R., Zhao, S. Y., Pang, Y.*, Gu, P.* Verteporfin-mediated on/off photoswitching functions synergistically to treat choroidal vascular diseases. Bioact. Mater. 2022, 14, 402.
11. Liu, J.#, Liu, Z. Y.#, Pang, Y.*, Zhou H. F.* The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases. J. Nanobiotechnology 2022, 20, 127.
12. Chen, L. B.#, Wu, F. #, Pang, Y.*, Yan, D., Zhang, S. Y., Chen, F. J., Wu, N. X., Gong, D. N., Liu, J. Y. *, Fu, Y. *, Fan, X. Q.* Therapeutic nanocoating of ocular surface. Nano Today 2021, 101309.
13. Chen,L. B.#, Yan, D.#, Wu, N. X., Yao, Q. K., Sun, H., Pang, Y.*, Fu, Y.* Injectable bio-responsive hydrogel for therapy of inflammation related eyelid diseases. Bioact. Mater. 2021, 6, 3062.
14. Yuan, Q. Y., Li, L. H., Peng, Y. Y., Zhuang, A., Wei, W., Zhang, D. D., Pang, Y.*, Bi, X. P.* Biomimetic nanofibrous hybrid hydrogel membranes with sustained growth factor release for guided bone regeneration. Biomater. Sci. 2021, 9, 1256.
15. Meng, L., Yang, F. M., Pang, Y.*, Cao, Z. P., Wu, F., Yan, D. Y. *, Liu, J. Y.* Nanocapping-enabled charge reversal generates cell-enterable endosomal-escapable bacteriophages for intracellular pathogen inhibition. Sci. Adv. 2022, abq2005.
16. Liu, R.#, Cao, Z. P. #, Wang, L., Wang, X. Y., Lin, S. S., Wu, F.*, Pang, Y.*, Liu, J. Y.* Multimodal oncolytic bacteria by coating with tumor cell derived nanoshells. Nano Today, 2022, 45, 101537.
17. Wang, L.,Wang, X. Y., Yang, F. M., Liu, Y., Meng, L., Pang, Y.*, Zhang, M. M., Chen, F. J., Pan, C., Lin, S. S., Zhu, X. Y. *, Leong, K. W., Liu, J. Y. * Systemic antiviral immunization by virus-mimicking nanoparticles-decorated erythrocytes. Nano Today 2021, 101280.
18. Geng Z. M.#, Chen F. J.#, Wang X. Y., Wang, L., Pang, Y. *, Liu J. Y.* Combining anti-PD-1 antibodies with Mn2+-drug coordinated multifunctional nanoparticles for enhanced cancer therapy. Biomaterials 2021, 275, 120897.
19. Hou, W. L., Li, J. J., Cao, Z. P., Lin, S. S., Pan, C., Pang Y. *, Liu, J. Y.* Decorating bacteria with a therapeutic nanocoating for synergistically enhanced biotherapy. Small 2021, 2101810.
20. Wu, F., Pang, Y.*, Liu, J. Y.*. Swelling-strengthening hydrogels by embedding with deformable nanobarriers. Nat. Commun. 2020, 11, 4502.
21. Cao, Z. P., Cheng, S. S., Wang, X. Y., Pang, Y.*, Liu, J. Y.* Camouflaging bacteria by wrapping with cell membranes. Nat. Commun. 2019, 10, 3452.
22. Pang, Y., Liu, J. Y., Moussa, Z. L., Collins, J. E., McDonnell, S., Hayward, A. M., Langer, R. S., Traverso, G. * Endoscopically-injectable shear-thinning hydrogels facilitating polyp removal. Adv. Sci. 2019, 1901041.
23. Pang, Y.#, Liu, J. Y.#, Qi, Y. Z.#, Li, X. H., Chilkoti, A*. A Modular Method for the High-Yield Synthesis of Site-Specific Protein–Polymer Therapeutics. Angew. Chem., Int. Ed. 2016, 55, 10296. Very Important Paper, VIP.

主持或参与科研项目
先后获得国家自然科学基金青年、面上项目、上海市教委东方学者、上海交通大学医学院地高大双百人计划以及转化医学国家重大科技基础设施(上海)开放课题项目等多个项目的资助。

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